Description

Principles of Pharmacology, offers an integrated mechanism-based and systems-based approach to contemporary pharmacology and drug development. An easy-to-follow format helps first- and second-year students grasp challenging concepts quickly and efficiently. Each chapter presents a clinical vignette illustrating a therapeutic problem within a physiologic or biochemical system; followed by a discussion of the biochemistry, physiology, and pathophysiology of the system; and concluding with a presentation of the pharmacology of the drugs and drug classes that activate or inhibit the system by interacting with specific molecular and cellular targets. Chapters are integrated into sections that focus on organ systems and therapeutic areas of highest importance. Clear, concise illustrations highlight key points, and drug summary tables offer quick access to essential information. This book provides an introduction into the basic principles of pharmacology and toxicology. Pharmacology and toxicology deal with the effects of biologically active compounds on physiological processes. An important part of this book consists of a practical in which students perform a clinical trial on the effects of nutrients on the kinetics of a drug.