Basic Principles of Drug Discovery and Development presents the multifaceted process of identifying a new drug in the modern era, providing comprehensive explanations of enabling technologies such as high throughput screening, structurebased drug design, molecular modeling, pharmaceutical profiling, and translational medicine, all areas that have become critical steps in the successful development of marketable therapeutics. The book introduces the fundamental principles of drug discovery and development, also discussing important drug targets by class, in vitro screening methods, and medicinal chemistry strategies in drug design. It is designed to enable new scientists to rapidly understand the key fundamentals of drug discovery.
1. The Drug Discovery Process: From Ancient Times to the Present Day,
2. Classical Targets in Drug Discovery,
3. In vitro Screening Systems,
4. Medicinal Chemistry.